Reirradiation of Recurrent Pediatric Brain Tumors after Initial Proton Therapy
نویسندگان
چکیده
منابع مشابه
Reirradiation of relapsed brain tumors in children.
AIM The aim of this study was to evaluate toxicity and response to fractionated reirradiation (FR) of relapsed primary brain tumors in children. BACKGROUND The treatment options for recurrent brain tumors in children previously irradiated are limited. Reirradiation is performed with fear due to the cumulative late CNS toxicity and the lack of a significant chance of cure. MATERIALS AND METH...
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Cancer is a major cause of childhood death, with central nervous system (CNS) neoplasms being the second most common pediatric malignancy, following hematological cancer. Treatment of pediatric CNS malignancies requires multimodal treatment using a combination of surgery, chemotherapy, and radiotherapy, and advances in these treatments have given favorable results and longer survival. However, ...
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Studies of RT as definitive treatment in primary and recurrent skin cancers consistently report high rates of local control despite extremely variable total doses and fractionation schedules [1-6]. With the increase of life expectancy, many patients develop second primary tumors within or close to previous RT area or late in-field recurrences [7]. Moreover, surgical options are frequently compr...
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Proton beam therapy (PBT) is a potential new alternative to treatment with photon radiotherapy that may reduce the risk of late toxicity and secondary cancer, especially for pediatric tumors. The goal of this study was to evaluate the long-term benefits of PBT in cancer survivors. A retrospective observational study of pediatric patients who received PBT was performed at four institutions in Ja...
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Background This phase II trial was designed to assess the response rate, survival benefits and toxicity profile of temozolomide, and brain reirradiation using conformal radiotherapy (CRT) for recurrent grade II brain glioma. Between February 2006 and June 2009, 18 patients with recurrent low grade glioma, and two with recurrent ependymoma were enrolled in the study. Patients had to show unequiv...
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ژورنال
عنوان ژورنال: International Journal of Particle Therapy
سال: 2016
ISSN: 2331-5180
DOI: 10.14338/ijpt-15-00036